Progesterone 300 mg sustained-release (SR) tablets are primarily used to supplement or replace endogenous progesterone in women with hormonal imbalance or deficiency. They help regulate the menstrual cycle, support the luteal phase, and are widely prescribed in infertility treatments, especially during assisted reproductive techniques (ART) such as IVF. The medication also plays a key role in maintaining early pregnancy by stabilizing the endometrium and reducing the risk of threatened miscarriage. Additionally, it is used in hormone replacement therapy (HRT) alongside estrogen to prevent endometrial hyperplasia in postmenopausal women.
Indications :
Luteal phase deficiency
Infertility treatment (IVF/ART support)
Threatened or recurrent miscarriage
Secondary amenorrhea
Hormone replacement therapy (with estrogen)
Premenstrual syndrome (PMS)
Dysfunctional uterine bleeding (due to hormonal imbalance)
Side Effects :
Drowsiness or dizziness 😴
Headache
Breast tenderness
Bloating or abdominal discomfort
Mood swings / irritability
Nausea
Vaginal spotting or discharge
Rare: allergic reactions, severe depression, jaundice
Precautions :
Avoid alcohol and driving if feeling drowsy
Use cautiously in liver disease patients
Inform doctor if history of:
Blood clots (DVT/PE)
Breast cancer or hormone-sensitive tumors
Depression
Not for use in undiagnosed vaginal bleeding
Monitor regularly during long-term therapy
Take preferably at bedtime (reduces dizziness)
Storage Guide :
Store below 25°C
Keep in a cool, dry place away from sunlight
Do not refrigerate unless specified
Keep out of reach of children
Do not use after expiry date
