Isosorbide Dinitrate 20 mg and Hydralazine Hydrochloride 37.5 mg is a combination medication used in the management of heart failure. Isosorbide Dinitrate is a vasodilator that relaxes blood vessels, reducing the workload on the heart and improving blood flow. Hydralazine Hydrochloride is an arterial vasodilator that lowers vascular resistance and helps the heart pump blood more efficiently. Together, these medicines help improve cardiac function, reduce symptoms such as shortness of breath and fatigue, enhance exercise tolerance, and decrease the risk of hospitalization in patients with chronic heart failure when used as prescribed by a healthcare professional.
Indications :
- Chronic heart failure (Heart Failure with Reduced Ejection Fraction – HFrEF)
- Adjunct therapy in patients with symptomatic heart failure
- Patients who cannot tolerate ACE inhibitors or ARBs
- Management of heart failure-associated symptoms such as breathlessness and fatigue
- Reduction of cardiac workload through vasodilation
- Improvement of exercise capacity and quality of life in heart failure patients
Common Side Effects :
- Headache
- Dizziness
- Low blood pressure (Hypotension)
- Flushing
- Rapid heartbeat (Tachycardia)
- Nausea
- Weakness or fatigue
- Lightheadedness, especially when standing up suddenly
Storage Instructions :
- Store below 25°C in a cool and dry place.
- Protect from moisture, heat, and direct sunlight.
- Keep the tablets in their original packaging until use.
- Keep out of reach of children.
Prescription Drug: This medication should be used strictly under the supervision of a qualified healthcare professional.
